Publications

  1. Spatial propagation of temperate phages within and among biofilms

    Winans JB, Zeng L, Nadell CD†. (2024). bioRxiv www.biorxiv.org/content/10.1101/2023.12.20.571119v4. (†corresponding)

  2. Dispersal of a dominant competitor can drive multispecies coexistence in biofilms

    Holt JD, Schultz D, Nadell CD†. (2024). Current Biology 34: 1-14 (†corresponding)

  3. Pseudomonas aeruginosa surface motility and invasion into competing communities enhance interspecies antagonism

    Sánchez-Peña A, Winans JB, Nadell CD, Limoli DH. (2024). mBio: e00956-24

  4. Bacteriophage specificity is impacted by interactions between bacteria

    Bisesi AT, Möbius W, Nadell CD, Hansen EG, Bowden SD, Harcombe WR. (2024). mSystems: e01177-23

  5. Community composition and the environment modulate the population dynamics of type VI secretion in human gut bacteria

    Robitaille S, Simmons EL, Verster AJ, McClure EA, Royce DB, Trus E, Swartz K, Schultz D, Nadell CD, Ross BD. (2023). Nature Ecology and Evolution 7: 2092-2107

  6. Bacterial defences: mechanisms, evolution, and antimicrobial resistance

    Smith WPJ, Wucher BR, Nadell CD, Foster KR. (2023). Nature Reviews Microbiology : https://doi.org/10.1038/s41579-023-00877-3

  7. Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation

    Wucher BR, Winans JB, Elsayed M, Kadouri DE, Nadell CD†. (2023). PNAS 120(6): e2212650120 (†corresponding)

    – Feature journal cover and commentary by Thomas Platt

    – Featured paper in episode #282 of This Week in Microbiology (TWiM – ASM offical podcast)

  8. Multispecies biofilm architecture determines bacterial exposure to phages

    Winans J, Wucher BR, Nadell CD†. (2022). PLoS Biology 20(12): e3001913 (†corresponding)

  9. An RNA sponge controlling quorum sensing dynamics and biofilm formation in Vibrio cholerae

    Huber M, Lippegaus A, Melamed S, Siemers M, Wucher BR*, Nadell CD, Storz G, Papenfort K (2022). Nature Communications 13: 7585

  10. Social evolution of shared biofilm matrix components

    Tai J-S B, Mukherjee S, Nero T, Olson R, Tithof J, Nadell CD†, Yan J†. (2022). PNAS 119(27): e2123469119.  (†corresponding)

  11. VxrB influences antagonism within biofilms by controlling competition through extracellular matrix production and Type 6 Secretion

    Teschler JK, Jimenez-Siebert E, Jeckel H, Singh PK, Park JH, Pukatzki S, Nadell CD, Drescher K, Yildiz F. (2022). mBio e01885-22

    – Selected as a top paper of the year submitted by ASM Fellows

  12. Mechanisms underlying Vibrio cholerae biofilm formation and dispersion

    Teschler JK, Nadell CD, Drescher K, Yildiz FH. (2022). Annual Review of Microbiology 76: xx

  13. An alanine aminotransferase is required for biofilm-specific resistance of Aspergillus fumigatus to echinocandin treatment

    Kerkaert JD, Le Mauff F, Wucher BR, Beattie SR, Vesely EM, Sheppard DC, Nadell CD, Cramer RA. (2022). mBio 13(2): e02933-21

  14. Microbial interspecies associations in fracture-related infection

    Gitajn IL, Werth P, O’Toole RV, Mandarin J, Jevsevar D, Wise B, Rane A, Horton S, McClure EA, Ross B, Nadell CD. (2022). Journal of Orthopaedic Trauma 36(6): 309-316

  15. Differential surface competition and biofilm invasion strategies of Pseudomonas aeruginosa PA14 and PAO1

    Kasetty S*, Katharios-Lanwermeyer S*, O’Toole GA†, Nadell CD†. (2021). Journal of Bacteriology  (*co-first authors; †corresponding)

  16. Model systems to study the chronic, polymicrobial infections in Cystic Fibrosis: current approaches and exploring future directions.

    O’Toole GA, et al. (Dartmouth CF conference paper). (2021). mBio 12(5): e01763-21

  17. Matrix-trapped viruses can prevent invasion of bacterial biofilms by colonizing cells

    Bond MC, Vidakovic L, Singh PK, Drescher K, Nadell CD†. (2021). eLife 10: e65355   (†corresponding)

  18. Both Pseudomonas aeruginosa and Candida albicans accumulate greater biomass in dual-species biofilms under flow 

    Kasetty S, Mould DL, Hogan DA, Nadell CD† (2021). mSphere 6(3): e00416-21   (†corresponding)

  19. Let-7b-5p in vesicles secreted by human airways cells reduces biofilm formation and increases antibiotic sensitivity of P. aeruginosa

    Koeppen K, Nymon A, Barnaby R, Bashor L, Li Z, Hampton TH, Liefield AE, Kolling FW, LaCroix IS, Gerber S, Hogan DA, Kasetty K, Nadell CD, Stanton BA. (2021). PNAS 118(28): e2105370118

  20. Bacterial predation transforms the landscape and community assembly of biofilms

    Wucher BR, Elsayed M, Adelman JS, Kadouri KE, Nadell CD†(2021). Current Biology 31: 1-9   (†corresponding)

  21. A heterogeneously expressed gene family modulates the biofilm architecture and hypoxic growth of Aspergillus fumigatus

    Kowalski CH, Morelli KA, Stajich JE, Nadell CD, Cramer RA (2021). mBio 12(1): e03579-20

  22. Quantitative image analysis of microbial communities with BiofilmQ

    Hartmann R, Jeckel H, Jelli E, Singh PK,  Vaidya S, Bayer M, Rode DKH, Vidakovic L, Díaz-Pascual F, Fong JCN,  Dragoš A, Lamprecht O, Thöming JG, Netter N, Häussler S, Nadell CD, Sourjik V, Kovács ÁT, Yildiz FH, Drescher K. (2021). Nature Microbiology 6:151-156

  23. Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance

    Kowalski CH, Morelli KA, Schultz D, Nadell CD, Cramer RA. (2020). PNAS 36: 22473-22483

  24. Biofilm structure promotes the coexistence of phage-resistant and phage-susceptible bacteria

    Simmons EL*, Bond MC*, Koskella B, Drescher K, Bucci V, Nadell CD†. (2020)  mSystems 5(3):  e00877-19  (*co-first authors;  †corresponding)

  25. Vibrio cholerae filamentation promotes chitin surface attachment at the expense of competition in biofilms

    Wucher BR, Bartlett TM, Hoyos M, Papenfort K, Persat A, Nadell CD†. (2019)  PNAS 116(28): 14216-14221   (†corresponding)

  26. A conserved regulatory circuit controls large adhesins in Vibrio cholerae

    Kitts G, Giglio KM, Zamorano-Sánchez D, Park JH, Townsley L, Cooley RB, Wucher BR, Klose KE, Nadell CD, Yildiz FH, Sondermann H. (2019). mBio 10(6): e0822-19

  27. Fungal biofilm morphology impacts hypoxia fitness and disease progression

    Kowalski CH, Kerkaert KD, Liu K-W, Bond MC, Hartmann R, Nadell CD, Stajich J, Cramer RA  Nature Microbiology 4(12): 2430-2441

  28. Breakdown of biofilm architecture in response to antibiotics facilitates community invasion

    Diaz-Pascual F, Hartmann R, Lempp M, Vidakovic L, Song B, Yildiz F, Dunkel J, Link H, Nadell CD, Drescher K. (2019)  Nature Microbiology 4: 2136-2145

  29. Cellular advective-diffusion drives the emergence of bacterial surface colonization patterns and heterogeneity

    Rossy T, Nadell CD†, Persat A† (2019) Nature Communications 10:2471  (†corresponding)

  30. Cell adhesion and fluid flow jointly initiate genotype spatial distribution in biofilms

    Garcia-Martinez R, Nadell CD†, Hartmann R, Drescher K, Bonachela J†.  (2018). PLoS Computational Biology 14(4): e1006094  (†corresponding)

  31. Phage mobility is a core determinant of phage-bacteria coexistence in biofilms

    Simmons M, Drescher K, Nadell CD†, Bucci V† (2018). ISME Journal 12: 531-543   (†corresponding)

  32. Dynamic biofilm architecture confers individual and collective mechanisms of viral protection

    Vidakovic L, Singh PK, Hartmann R, Nadell CD†, Drescher K† (2018). Nature Microbiology 3: 26-31    (†corresponding)

  33. Vibrio cholerae combines individual and collective sensing to trigger biofilm dispersal

    Singh PK, Hartmann R, Bartolomej S, Nadell CD, Drescher K. (2017). Current Biology 27: 1-8

  34. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion.

    Yan J, Nadell CD, Stone HA, Wingreen NS, Bassler BL. (2017). Nature Communications 8:327

  35. Flow environment and matrix structure interact to shape spatial competition in P. aeruginosa biofilms.

    Nadell CD*, Ricaurte D*, Yan J, Drescher K, Bassler B (2017).  eLife 6: e21855    (*co-first authors)

  36. Environmental fluctuation governs selection for plasticity in biofilm production.

    Yan J*, Nadell CD*, Bassler B (2017). ISME Journal: doi:10.1038/ismej.2017.33   (*co-first authors)

  37. An emerging grip on the growth of grounded bacteria.

    Nadell CD, Hartmann R, Drescher K (2016). ACS Nano 10:9109-9110   (commentary)

  38. Spatial structure, cooperation, and competition in biofilms.

    Nadell CD†, Drescher K, Foster KR†. (2016). Nature Reviews Microbiology 14: 589-600   (†corresponding)

  39. Architectural transitions in Vibrio cholerae biofilm development at single-cell resolution.

    Drescher K, Dunkel J, Nadell CD, van Teeffelen S, Grnja I, Wingreen NS, Stone HA, Bassler BL. (2016). PNAS 113(4): E2066-2072

  40. The mechanical world of bacteria.

    Persat A, Nadell CD, Kim MK, Ingremeau F, Siryaporn A, Drescher K, Wingreen NS, Bassler BL, Gitai Z, Stone HA. (2015). Cell 161(5): 988-997

  41. Extracellular matrix structure governs invasion resistance in bacterial biofilms.

    Nadell CD, Drescher K, Wingreen NS, Bassler BL (2015). ISME Journal 9: 1700-1709

  42. Adhesion as a weapon in microbial competition.

    Schluter J, Nadell CD, Bassler BL, Foster KR (2015). ISME Journal 9: 139-149

  43. Solutions to the public goods dilemma in bacterial biofilms.

    Drescher K, Nadell CD, Stone HA, Wingreen NS, Bassler BL (2014). Current Biology 24: 50-55

  44. Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria.

    van Ditmarsch D, Boyle KE, Sakhtah H, Oyler J, Nadell CD, Déziel E, Dietrich LEP, Xavier JB (2013). Cell Reports 4: 1-12

  45. Cutting through the complexity of cell collectives.

    Nadell CD†, Bucci V, Drescher K, Levin, SA, Bassler BL, Xavier JB (2013). Proceedings of the Royal Society B 280: 20122770   (†corresponding)

  46. Mutually helping microbes can evolve by hitchhiking.

    Nadell CD† & Foster KR (2012). PNAS 109(47): 19037-19038  (commentary) (†corresponding)

  47. Mathematical and computational challenges in the study of complex adaptive microbial systems.

    Levin SA, Bonachela JA, Nadell CD (2012). The Social Biology of Microbial Communities pp. 361-385. NAS Press.

  48. A fitness trade-off between local competition and dispersal in Vibrio cholerae biofilms.

    Nadell CD & Bassler BL (2011). PNAS 108(34): 14181-14185

  49. The evolution of bacteriocin production in bacterial biofilms.

    Bucci V, Nadell CD, Xavier JB (2011). American Naturalist 178(6): E162-E173

  50. Universality in bacterial colonies.

    Bonachela JA, Nadell CD, Xavier JB, Levin SA (2011). Journal of Statistical Physics 144: 303-315

  51. Emergence of spatial structure in cell groups and the evolution of cooperation.

    Nadell CD, Foster KR, Xavier JB. (2010). PLoS Computational Biology 6(3): e1000716

  52. The sociobiology of biofilms.

    Nadell CD, Xavier JB, Foster KR. (2009). FEMS Microbiology Reviews 33: 206-224

  53. Observing bacteria through the lens of social evolution.

    Nadell CD, Bassler BL, Levin SA (2008). Journal of Biology 7: 27

  54. The evolution of quorum sensing in bacterial biofilms.

    Nadell CD, Xavier JB, Levin SA, Foster KR (2008). PLoS Biology 6(1): e14